People at the ORC

Dr Tracy Melvin

email: tm@orc.soton.ac.uk
tel: +44 23 8059 6505

Reader

Member of groups

• Optical Biosensors & Biophotonics

About Dr Tracy Melvin

Tracy Melvin obtained her PhD from University College London. After post-docs at the University of Illinois, Urbana-Champaign, USA and the Max Planck Institut fuer Strahlenchemie, Germany, she worked in the MRC Radiation and Genome Stability Unit on direct ionisation and enzymatic detection of DNA damage. After researching in the area of charge-migration in DNA, she became interested in the interface of microsystems and microelectronics with biochemistry and took up a research post in the CNRS working at the Centre de Biophysique Molelaire and the Laboratoire de Physique et Metrologie des Oscillateurs, France.

Since September 2000 she has been at the University of Southampton and has research interests in the areas of optical microdevices for bioanalysis and self-assembled photonic and electronic devices. The focus of her research is to create technologies to provide the potential to answer bioscience questions, that are difficult or cannot be answered in any other way. This is achieved by developing novel methodology and devices, some of which was originally conceived for optical telecommunications applications. Her research crosses the medical science – micro-optical device interface and includes bionanotechnology methods.

There are 44 publications in ORC database for 'Melvin, T.'

• 4833 —  K.Pechstedt, T.Whittle, J.J.Baumberg, T.MelvinPhotoluminescence of colloidal CdSe/ZnS quantum dots: the critical effect of water
  J. Phys. Chem C 2010 Vol.114 pp.12069-12077
  [Abstract]  
• 4812 —  N.M.B.Perney, J.Hughes, P.Horak, N.A.Hanley, T.MelvinOptical classification of human embryonic stem cells
  UKNSCN Nottingham 12-14 Jul 2010  
• 4758 —  P.Glynne-Jones, M.Hill, F.Zhang, L.Dong, J.Wilkinson, T.Brown, T.Melvin, N.HarrisMulti-modal particle manipulator to enhance bead-based bioassays
  Ultrasonics 2010 Vol.50(2) pp.235-239
  [Abstract]  
• 4714 —  L.M.Braddick, P.J.Garland, M.F.Praeger, T.MelvinMicropatterning of integrated sensors with antigens for binding inhibition assays
  Biosensors 2010 Glasgow 26-28 May 2010 0891  
• 4713 —  N.M.B.Perney, P.Horak, N.Hanley, T.MelvinMammalian cell orientation in optical tweezers
  Biosensors 2010 Glasgow 26-28 May 2010 0802 (accepted)  
• 4501 —  T.Humphreys, J.Andersson, U.Sodervall, T.MelvinWorld-to-chip interconnects for efficient loading of genomic DNA into microfluidic channels
  Journal of Micromechanics and Microengineering 2009 Vol.19 pp.105024
  [Abstract]  
• 4458 —  P.Glynne-Jones, R.Boltryk, M.Hill, F.Zhang, L.Dong, J.S.Wilkinson, T.Brown, T.Melvin, N.HarrisMulti-modal particle manipulator to enhance bead-based bioassays
  International Congress on Ultrasonics Santiago, Chile 11-17 Jan 2009
  [Abstract]  
• 4246 —  P.Glynne-Jones, R.J.Boltryk, M.Hill, F.Zhang, L.Dong, J.S.Wilkinson, T.Melvin, N.R.Harris, T.BrownFlexible acoustic particle manipulation device with integrated optical waveguide for enhanced microbead assays
  Analytical Sciences 2009 Vol.25(2) pp.285-291
  [Abstract]  
• 4152 —  P.Glynne-Jones, M.Hill, R.J.Townsend, N.R.Harris, J.S.Wilkinson, T.MelvinAn integrated multimodal acoustic particle manipulator and optical evanescent field waveguide
  Journal of Acoustic Society of America 2008 Vol.123(5 Pt2) pp.3925 (Paper 5pPAa2 in Acoustics '08, 4 July, Paris )
  [Abstract]  
• 4113 —  C.F.Chau, T.MelvinFabrication of macroporous polysilicon by nanosphere lithography
  Journal of Micromechanics & Microengineering 2008 Vol.18(6) pp.064012
  [Abstract]  
• 4072 —  D.Friedrich, C.Please, T.MelvinOptimisation of analyte transport in integrated microfluidic affinity sensors for the quantification of low levels of analyte
  Sensors and Actuators B 2008 Vol.131(1) pp.323-332
  [Abstract]  
• 4031 —  T.MelvinOptical biosensing: future possibilities
  Expert Review of Opthalmology 2007 Vol.2(6) pp.883-887 (Editorial)
  [Abstract]  
• 3941 —  C.F.Chau, T.MelvinFabrication of macroporous polysilicon by using nanosphere lithography
  18th Meeting on Micromachining, Micromechanics and Microsystems (MME 2007) Guimaraes, Portugal 16-18 Sep 2007 pp.273-276
  [Abstract]  
• 3866 —  M.Hill, P.Glynne-Jones, R.J.Townsend, N.R.Harris, A.W.Cranny, T.Melvin, F.Zhang, J.S.WilkinsonNodal position in planar resonators for ultrasonic manipulation
  19th International Congress on Acoustics (ICA 2007) Madrid, Spain 2-7 Sep 2007
  [Abstract]  
• 3382 —  T.Melvin, L.Dyadshuka, A.Weld, H.Yin, A.Adam, T.Brown, S.Jaiswal, K.Boudakos, D.C.Smith, J.J.Baumberg, F.BooyDNA, nanoparticles and photons - new approaches for clinical diagnostics
  International Symposium on Biophotonics, Nanophotonics and Metamaterials Hangzhou, China Oct 16-18 2006 (Proceedings pp.20-21, 2006)
  [Abstract]  
• 3477 —  C.F.Chau, T.MelvinDesign and fabrication of passive mixing channels to be incorporated into a centrifugally driven microfluidic lab-on-a-disc
  PREP 2005 Lancaster, UK Mar 2005
  [Abstract]  
• 3476 —  M.Bahrami, A.G.R.Evans, J.S.Wilkinson, B.Husband, N.Sessions, T.MelvinFabrication and testing of a micro-fabricated PCR Device with an integrated fluorescence detector
  16th MicroMechanics Europe Workshop Gothenburg, Sweden 2005 pp.358-361
  [Abstract]  
• 3475 —  B.Husband, A.G.R.Evans, T.MelvinFluid dispensing using superparamagnetic beads
  16th MicroMechanics Europe Workshop, MME Gothenburg, Sweden 4-6 Sep 2005 Poster
  [Abstract]  
• 3474 —  H.B.Yin, T.Brown, J.S.Wilkinson, R.W.Eason, T.MelvinPhotonic generation of DNA micropatterns for haplotype analysis
  BioScience 2005 Glasgow Jul 2005
  [Abstract]  
• 3473 —  C.W.A.Johnson, H.Yin, M.G.Gore, T.MelvinProtein patterning on silicon (100)
  BioScience 2005 Glasgow Jul 2005 Poster
  [Abstract]  
• 3297 —  M.Bahrami, T.Melvin, J.S.Wilkinson, A.G.R.EvansPCR device with integrated thermal cycling and fluorescence detection elements
  Smart Sensors, Actuators, and MEMS II Sevilla, Spain 9 May 2005 in Proc. SPIE Vol.5836 (285)
  [Abstract]  
• 3244 —  L.Dyadyusha, H.Yin, S.Jaiswal, T.Brown, J.J.Baumberg, F.P.Booy, T.MelvinQuenching of CdSe quantum dot emission, a new approach for biosensing
  Chemical Communications 2005 Vol.25 pp.3201-3203
  [Abstract]  
• 3130 —  B.Husband, T.Melvin, A.G.R.EvansA superparamagnetic bead driven fluidic device
  Smart Sensors, Actuators, and MEMS II Seville, Spain 9 May 2005 5836 (Proceedings SPIE) (Invited)
  [Abstract]  
• 3695 —  B.Husband, M.Bu, V.Apostolopoulos, T.Melvin, A.G.R.EvansNovel actuation of an integrated peristaltic micropump
  Microelectronic Engineering 2004 Vol.73-74 pp.858-863
  [Abstract]  
• 3470 —  B.Husband, T.Melvin, A.G.R.EvansFluidic control using superparamagnetic beads
  15th Micromechanics Europe Workshop MME Leuven Belgium 5-7 Sep 2004 Poster
  [Abstract]  
• 3290 —  M.Bu, B.Husband, T.Melvin, G.Ensell, J.S.Wilkinson, A.EvansAn improved micro peristaltic pump for pumping air and its application in a micro PCR device
  Eurosensors Rome, Italy 12-15 Sep 2004 (Abstract unavailable)  
• 3289 —  M.Bahrami, T.Melvin, J.S.Wilkinson, A.G.R.EvansMicro-fabricated polymerase chain reaction device with integrated fluorescence detection elements
  15th MicroMechanics Europe Workshop Leuven Belgium 2004 pp.203-206
  [Abstract]  
• 3241 —  B.Husband, M.Bu, A.G.R.Evans, T.MelvinInvestigation for the operation of an integrated peristaltic micropump
  Journal of Micromechanics and Microengineering 2004 Vol.14(9) pp.S64-69
  [Abstract]  
• 3083 —  M.Bahrami, T.Melvin, J.S.Wilkinson, A.G.R.EvansOptical filter technologies for integration into a silicon microfabricated PCR device with a PN diode
  PREP 2004 Hertfordshire, England 6 Apr 2004
  [Abstract]  
• 2947 —  H.B.Yin, T.Brown, R.Greef, J.S.Wilkinson, T.MelvinChemical modification and micropatterning of Si(100) with oligonucleotides
  Microelectronic Engineering 2004 Vol.73-4 pp.830-836
  [Abstract]  
• 2946 —  A.M.Weld, H.B.Yin, T.MelvinDetection of DNA-gold nanoparticle hybrids on patterned surfaces
  Postgraduate Conference on Biomedical Engineering and Medical Physics (PGBIOMED'04) Southampton Aug 2004
  [Abstract]  
• 2923 —  M.Bu, T.Melvin, G.J.Ensell, J.S.Wilkinson, A.G.R.EvansA new masking technology for deep glass etching and its microfluidic application
  Sensors and Actuators A: Physical 2004 Vol.115(2-3) pp.476-482
  [Abstract]  
• 2917 —  H.B.Yin, T.Brown, J.S.Wilkinson, R.W.Eason, T.MelvinSubmicron patterning of DNA oligonucleotides on silicon
  Nucleic Acids Research 2004 Vol.32(14) Article no. e118
  [Abstract]  
• 2870 —  H.B.Yin, T.Brown, R.Greef, S.Mailis, R.W.Eason, J.S.Wilkinson, T.MelvinPhoto-patterning of DNA oligonucleotides on silicon surfaces with micron-scale dimensions
  Biophotonics New Frontier: From Genome to Proteome Strasbourg, France 27-29 Apr 2004 6 pp.1-8 in Proc. SPIE, 5461, Michel D. Faupel, Patrick Meyrueis, Editors, (2004)
  [Abstract]  
• 3237 —  M.Bu, B.Husband, T.Melvin, G.J.Ensell, N.P.Pham, P.M.Sarro, J.S.Wilkinson, A.G.R.EvansFabrication of a microfluidic chip for PCR applications
  14th MicroMechanics Europe Workshop Delft, The Netherlands 2-4 Nov 2003 pp.119-122 Poster
  [Abstract]  
• 2903 —  M.Bu, T.Melvin, G.Ensell, J.Wilkinson, A.G.R.EvansFabrication of a micro peristaltic pump
  PREP 2003 University of Exeter 14-16th Apr 2003
  [Abstract]  
• 2882 —  B.Husband, M.Bu, V.Apostolopoulos, T.Melvin, A.G.R.EvansInvestigation for the operation of an integrated peristaltic micropump
  14th MicroMechanics Europe Workshop Delft, Netherlands 2-4 Nov 2003 Poster
  [Abstract]  
• 2834 —  H.B.Yin, T.Brown, S.Mailis, J.S.Wilkinson, T.MelvinChemical modification and patterning of Si(100) using interference photolithography
  29th International Conference on Micro- and Nano-Engineering Cambridge 22-25 Sep 2003 pp.422-423  
• 2833 —  H.B.Yin, T.Brown, S.Mailis, J.S.Wilkinson, T.MelvinMicro/submicro-patterning of DNA on Si(100) surface
  Roy. Soc. of Chem. Frontiers in chemical biology: Biomolecular dynamics and force generation Manchester 4-6 Sep 2003 pp.12  
• 2689 —  M.Bu, T.Melvin, G.Ensell, J.S.Wilkinson, A.G.R.EvansDesign and theoretical evaluation of a novel microfluidic device to be used for PCR
  Journal Micromechanics Microengineering 2003 Vol.13(4) pp.S125-S130 Special issue, articles from 13th MicroMechanics Europe Workshop (MME 02)
  [Abstract]  
• 2654 —  M.Bu, T.Melvin, G.Ensell, J.S.Wilkinson, A.G.R.EvansNew deep glass etching technology
  Eurosensors 17 Guimares, Portugal 21-24 Sep 2003
  [Abstract]  
• 2784 —  M.Bu, T.Melvin, A.Evans, J.WilkinsonDesign and simulation of a micro pump PCR chip
  MME 02 Romania 6-8th October 2002
  [Abstract]  
• 2625 —  E.Privat, T.Melvin, F.Merola, G.Schweizer, S.Prodhomme, U.Asseline, P.VignyFluorescent properties of oligonucleotide-conjugated thiazole orange probes
  Photochemistry and Photobiology 2002 Vol.75(3) pp.201-210
  [Abstract]  
• 2325 —  E.Privat, T.Melvin, U.Asseline, P.VignyOligonucleotide-conjugated thiazole orange probes as "light-up" probes for messenger ribonucleic acid molecules in living cells
  Photochemistry and Photobiology 2001 Vol.74(4) pp.532-541
  [Abstract]  

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